Description
HemaPAC-SR-SLE – Serum from Donors with Systemic Lupus Erythematosus
HemaPAC-SR-SLE is cryopreserved serum collected from donors diagnosed with Systemic Lupus Erythematosus (SLE). SLE donor material is widely used in autoimmune research because the immune systems of lupus patients carry distinct features — altered T cell subset distributions, abnormal regulatory T cell function, chronic inflammatory priming, and dysfunctional signaling cascades — that healthy donor controls do not represent.
Why SLE Donor Serum
Manufacturing processes, assays, and therapeutic candidates optimized using healthy donor material can fail to translate to patient samples. Working directly with SLE donor serum allows researchers to study disease-specific biology, identify and validate biomarkers, screen drug candidates against patient-representative material, and de-risk programs targeting autoimmune indications.
Documentation
Donors are enrolled under IRB-approved protocols with verified clinical diagnosis of SLE. Each sample is accompanied by disease history, treatment background, inclusion and exclusion criteria documentation, and demographic profile. Every lot ships with a Certificate of Analysis.
Configuration
1 mL aliquots, cryopreserved, stored at <−150°C in liquid nitrogen vapor phase. For preclinical research use only and not for use in humans.
Other Indications Available
OrganaBio sources disease-state donor material across autoimmune (lupus, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, Crohn’s, psoriasis, celiac), oncology, and chronic inflammatory indications. Contact the scientific team to confirm availability for specific conditions.
For more on lupus donor material in cell therapy development, see Breaking the Healthy Donor Paradigm.
