Description
HemaPAC-PL-SLE – Plasma from Donors with Systemic Lupus Erythematosus
HemaPAC-PL-SLE is cryopreserved plasma collected from donors diagnosed with Systemic Lupus Erythematosus (SLE). Plasma from lupus donors carries the proteomic signature of chronic autoimmune inflammation, including elevated levels of cytokines such as IL-6, IL-17, and IFN-γ that have shaped donor immune cells over time.
Why SLE Donor Plasma
Therapeutic candidates and assays validated using healthy donor plasma can perform differently when exposed to the inflammatory milieu of patient samples. SLE plasma supports work on biomarker discovery, immune signaling studies, autoantibody profiling, and disease-specific assay development. It is also used as a representative biological matrix for assay validation in autoimmune drug development programs.
Documentation
Donors are enrolled under IRB-approved protocols with verified clinical diagnosis of SLE. Each sample is accompanied by disease history, treatment background, inclusion and exclusion criteria documentation, and demographic profile. Every lot ships with a Certificate of Analysis.
Configuration
1 mL aliquots, cryopreserved, stored at <−150°C in liquid nitrogen vapor phase. For preclinical research use only and not for use in humans.
Other Indications Available
Disease-state plasma is available across autoimmune (lupus, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, Crohn’s, psoriasis, celiac), oncology, and chronic inflammatory indications. Contact the scientific team to confirm availability for specific conditions.
For more on lupus donor material in cell therapy development, see Breaking the Healthy Donor Paradigm.
